Research Articles
Powering Microbiome Discovery: A Practical Guide to Dirichlet-Multinomial Power Analysis for Clinical and Taxonomic Studies
This comprehensive guide addresses the critical need for robust statistical power calculations in microbiome and taxonomic data analysis, where high-dimensional, compositional count data is the norm.
Beyond the Noise: A Practical Guide to Small-Sample Microbiome Research for Robust Biomarker Discovery
This article provides a comprehensive framework for designing, analyzing, and validating microbiome studies constrained by small sample sizes, a common yet critical challenge in biomedical research.
Power in the Gut: DS-FDR vs. Benjamini-Hochberg for Microbiome Differential Abundance
This article provides a comprehensive analysis of the power characteristics of the Data-adaptive Structure-adaptive False Discovery Rate (DS-FDR) procedure compared to the classic Benjamini-Hochberg (BH) method in microbiome differential abundance...
DNA/RNA Shield: The Game-Changer for Room Temperature Microbiome Sample Preservation and Stabilization
This article provides a comprehensive guide for researchers and drug development professionals on DNA/RNA Shield technology for stabilizing microbiome samples at room temperature.
Beyond Contamination: The Essential Guide to DNA-Free Reagents for Accurate Microbiome Research
This comprehensive guide explores the critical role of DNA-free reagents in microbiome DNA extraction.
A Complete Guide to DNA-free Equipment Decontamination Protocols for Next-Generation Research
This article provides a comprehensive, modern framework for eliminating DNA contamination from laboratory collection equipment, critical for high-sensitivity genomic and diagnostic workflows.
The Essential Guide to DNA Extraction QC for Robust Microbiome Research: From Basics to Best Practices
This comprehensive guide addresses the critical role of DNA extraction quality control (QC) in ensuring the reliability, reproducibility, and validity of microbiome study data.
Overcoming the Biomass Bottleneck: A Comprehensive Guide to DNA Extraction from Low-Biomass Samples
This article provides a detailed guide for researchers, scientists, and drug development professionals on extracting high-quality DNA from challenging low-biomass samples.
Extracting Microbial Truth: A Complete Guide to DNA Protocols for 16S vs. Shotgun Metagenomic Sequencing
This definitive guide provides researchers and biopharma professionals with a comprehensive, current analysis of DNA extraction protocols tailored for 16S rRNA gene sequencing and whole-genome shotgun metagenomics.
Optimizing DNA Extraction for Stool Microbiome Analysis: A Comprehensive Guide for Biomedical Researchers
This article provides a detailed, up-to-date guide on DNA extraction methods for stool microbiome analysis, tailored for researchers, scientists, and drug development professionals.